WHAT IS REZUROCK?
REZUROCK is a medicine that can help to rebalance your immune system
REZUROCK blocks a specific protein in the body that is involved in inflammation and fibrosis. This may help to decrease symptoms of chronic GVHD like inflammation and scarring.
About the ROCK2 pathway
Many systems in the body work through what are called "PATHWAYS." These pathways are a series of actions that take place among cells and molecules within the body. One such pathway is called "ROCK2."
In people with chronic GVHD, this ROCK2 pathway has been shown to be too active. This leads to a decrease in cells and molecules that help keep the immune system in check and an increase in cells and molecules that cause inflammation and fibrosis. The result is an immune system that is OUT OF BALANCE.
Treatment of chronic GVHD
Your doctor may try different medicines, including immunosuppressants, to help treat chronic GVHD. However, for some people that might not be enough, and they will need a different approach.
REZUROCK can help rebalance your immune system by blocking the ROCK2 pathway in your body. This may reduce the inflammation and fibrosis that can happen with chronic GVHD.
LEARN MORE ABOUT HOW CHRONIC GVHD CAN AFFECT YOUR LIFE
GVHD, graft-versus-host disease.
MAT-XU-2305027 (v2.0)
Date of Preparation: February 2025
